Adobe says that future versions of its Creative Suite (currently at version 4) will run only on Intel-based Mac computers; Creative Suite 5+ will not work if you have a PowerPC-based Mac system. This decision was based on Apple withdrawing support for the PowerPC chip set with its new operating systems, beginning with Mac OS X Snow Leopard (V10.6). With Apple’s future development focused on Intel Macs, Adobe is aligning its resources accordingly.

Customers who own Creative Suite 3 and Creative Suite 4 will still be able to use the software on either a PowerPC-based Mac or an Intel-based Mac and do not have to upgrade their software. However, Adobe will not be developing for this platform other than for critical issues that may arise. For more information on this announcement, see the Creative Suite 4 FAQ.

There's no official word yet on when Adobe will release the next version of the Creative Suite.

Note that this issue is limited to Macs and does not include the Windows operating system.